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1

Pathogenesis of juvenile idiopathic arthritis associated uveitis: the known and unknown

Kalinina Ayuso, Viera, Makhotkina, Nathalia, van Tent-Hoeve, Maretta, de Groot-Mijnes, Jolanda D.F., Wulffraat, Nico M., Rothova, Aniki, de Boer, Joke H.

Journal:

Survey of Ophthalmology

Year:

2014

Language:

english

File:

PDF, 252 KB

english, 2014

2

A randomized trial of parenteral methotrexate comparing an intermediate dose with a higher dose in children with juvenile idiopathic arthritis who failed to respond to standard doses of methotrexate

Nicolino Ruperto, Kevin J. Murray, Valeria Gerloni, Nico Wulffraat, Sheila Knupp Feitosa De Oliveira, Fernanda Falcini, Pavla Dolezalova, Maria Alessio, Ruben Burgos-Vargas, Fabrizia Corona, Richard V

Journal:

Arthritis & Rheumatism

Year:

2004

Language:

english

File:

PDF, 148 KB

english, 2004

3

SHARE – workpackage 5: evidence based recommendations for diagnosis and treatment of juvenile localized scleroderma and juvenile systemic sclerosis

Culpo, Roberta, Vastert, Sebastian J, Ravelli, Angelo, Wulffraat, Nico, Foeldvari, Ivan, Zulian, Francesco, Anton, Jordi, Avcin, Tadej, Baildam, Eileen, Boros, Christina, Chaitow, Jeffrey, Constantin,

Journal:

Pediatric Rheumatology

Year:

2014

Language:

english

File:

PDF, 271 KB

english, 2014

4

The role of placebo effects in immune-related conditions: mechanisms and clinical considerations

Smits, Rosanne M., Veldhuijzen, Dieuwke S., Wulffraat, Nico M., Evers, Andrea W. M.

Journal:

Expert Review of Clinical Immunology

Year:

2018

Language:

english

File:

PDF, 1.37 MB

english, 2018

5

Children and young people get rheumatic disease too

Egert, Yona, Egert, Tsipi, Costello, Wendy, Prakken, Berent J, Smith, Eve M D, Wulffraat, Nico M

Journal:

The Lancet Child & Adolescent Health

Year:

2018

Language:

english

File:

PDF, 95 KB

english, 2018

6

Towards European harmonisation of healthcare for patients with rare immune disorders: outcome from the ERN RITA registries survey

Papa, Riccardo, Cant, Andrew, Klein, Christoph, Little, Mark A., Wulffraat, Nico M., Gattorno, Marco, Ruperto, Nicolino

Journal:

Orphanet Journal of Rare Diseases

Year:

2020

Language:

english

File:

PDF, 275 KB

english, 2020

7

Identification of six novel WASP gene mutations in patients suffering from Wiskott-Aldrich syndrome

Rik A. Brooimans, Adriënne J.A.M van den Berg, Rienk Y.J. Tamminga, Tom Revesz, Nico M. Wulffraat, Ben J.M. Zegers

Journal:

Year:

2000

Language:

english

File:

PDF, 23 KB

english, 2000

8

Myeloid-related proteins 8 and 14 are specifically secreted during interaction of phagocytes and activated endothelium and are useful markers for monitoring disease activity in pauciarticular-onset juvenile rheumatoid arthritis

Michael Frosch, Anke Strey, Thomas Vogl, Nico M. Wulffraat, Wietse Kuis, Cord Sunderkötter, Erik Harms, Clemens Sorg, Johannes Roth

Journal:

Arthritis & Rheumatism

Year:

2000

Language:

english

File:

PDF, 840 KB

english, 2000

9

The Paediatric Rheumatology International Trials Organisation provisional criteria for the evaluation of response to therapy in juvenile dermatomyositis

Nicolino Ruperto, Angela Pistorio, Angelo Ravelli, Lisa G. Rider, Clarissa Pilkington, Sheila Oliveira, Nico Wulffraat, Graciela Espada, Stella Garay, Ruben Cuttica, Michael Hofer, Pierre Quartier, Jo

Journal:

Arthritis Care & Research

Year:

2010

Language:

english

File:

PDF, 99 KB

english, 2010

10

Expression of myeloid-related proteins 8 and 14 in systemic-onset juvenile rheumatoid arthritis

Michael Frosch, Thomas Vogl, Stephan Seeliger, Nico Wulffraat, Wietse Kuis, Dorothee Viemann, Dirk Foell, Clemens Sorg, Cord Sunderkötter, Johannes Roth

Journal:

Arthritis & Rheumatism

Year:

2003

Language:

english

File:

PDF, 110 KB

english, 2003

11

Monitoring neutrophil activation in juvenile rheumatoid arthritis by S100A12 serum concentrations

Dirk Foell, Helmut Wittkowski, Inga Hammerschmidt, Nico Wulffraat, Heinrike Schmeling, Michael Frosch, Gerd Horneff, Wietse Kuis, Clemens Sorg, Johannes Roth

Journal:

Arthritis & Rheumatism

Year:

2004

Language:

english

File:

PDF, 186 KB

english, 2004

12

Anakinra in mutation-negative NOMID/CINCA syndrome: Comment on the articles by Hawkins et al and Hoffman and Patel

Joost Frenkel, Nico M. Wulffraat, Wietse Kuis

Journal:

Arthritis & Rheumatism

Year:

2004

Language:

english

File:

PDF, 117 KB

english, 2004

13

S100A12 is a novel molecular marker differentiating systemic-onset juvenile idiopathic arthritis from other causes of fever of unknown origin

Helmut Wittkowski, Michael Frosch, Nico Wulffraat, Raphaela Goldbach-Mansky, Tilmann Kallinich, Jasmin Kuemmerle-Deschner, Michael C. Frühwald, Sandra Dassmann, Tuyet-Hang Pham, Johannes Roth, Dirk Fo

Journal:

Arthritis & Rheumatism

Year:

2008

Language:

english

File:

PDF, 141 KB

english, 2008

14

The myeloid-related proteins 8 and 14 complex, a novel ligand of toll-like receptor 4, and interleukin-1β form a positive feedback mechanism in systemic-onset juvenile idiopathic arthritis

Michael Frosch, Martina Ahlmann, Thomas Vogl, Helmut Wittkowski, Nico Wulffraat, Dirk Foell, Johannes Roth

Journal:

Arthritis & Rheumatism

Year:

2009

Language:

english

File:

PDF, 194 KB

english, 2009

15

Defective phosphorylation of interleukin-18 receptor β causes impaired natural killer cell function in systemic-onset juvenile idiopathic arthritis

Wilco de Jager, Sebastiaan J. Vastert, Jeffrey M. Beekman, Nico M. Wulffraat, Wietse Kuis, Paul J. Coffer, Berent J. Prakken

Journal:

Arthritis & Rheumatism

Year:

2009

Language:

english

File:

PDF, 340 KB

english, 2009

16

A phase II, multicenter, open-label study evaluating dosing and preliminary safety and efficacy of canakinumab in systemic juvenile idiopathic arthritis with active systemic features

Nicolino Ruperto, Pierre Quartier, Nico Wulffraat, Patricia Woo, Angelo Ravelli, Richard Mouy, Brigitte Bader-Meunier, Sebastiaan J. Vastert, Emanuele Noseda, Daniele D'Ambrosio, Jean Lecot, Abhijit C

Journal:

Arthritis & Rheumatism

Year:

2012

Language:

english

File:

PDF, 311 KB

english, 2012

17

Presence of ATM protein and residual kinase activity correlates with the phenotype in ataxia-telangiectasia: A genotype–phenotype study

Mijke M. M. Verhagen, James I. Last, Frans B. L. Hogervorst, Dominique F. C. M. Smeets, Nel Roeleveld, Frans Verheijen, Coriene E. Catsman-Berrevoets, Nico M. Wulffraat, Jan M. Cobben, Johan Hiel, Ewo

Journal:

Year:

2012

Language:

english

File:

PDF, 383 KB

english, 2012

18

Hepatic GVHD after HLA-haploidentical bone marrow transplantation in children with severe combined immunodeficiency: the effect of ursodeoxycholic acid

NICO M. WULFFRAAT, ELIE HADDAD, MALIKA BENKERROU, WIM G. M. SPLIET, NATACHA PATEY, ALAIN FISCHER, BABETTER. DE GRAEFF-MEEDER

Journal:

British Journal of Haematology

Year:

1997

Language:

english

File:

PDF, 849 KB

english, 1997

19

Functional consequences of perforin gene mutations in 22 patients with familial haemophagocytic lymphohistiocytosis

Jérôme Feldmann, Françoise Le Deist, Marie Ouachée-Chardin, Stéphanie Certain, Sarah Alexander, Pierre Quartier, Elie Haddad, Nico Wulffraat, Jean Laurent Casanova, Stéphane Blanche, Alain Fischer, Ge

Journal:

British Journal of Haematology

Year:

2002

Language:

english

File:

PDF, 203 KB

english, 2002

20

Joint contractures in the absence of inflammation may indicate mucopolysaccharidosis

Rolando Cimaz, Giovanni Valentino Coppa, Isabelle Koné-Paut, Bianca Link, Gregory M Pastores, Maria Rua Elorduy, Charles Spencer, Carter Thorne, Nico Wulffraat, Bernhard Manger

Journal:

Pediatric Rheumatology

Year:

2009

Language:

english

File:

PDF, 1.20 MB

english, 2009

21

Prediction of clinical non-response to methotrexate treatment in juvenile idiopathic arthritis

Pieter E H Van Dijkhuizen, Maja Bulatović, Marloes W Heijstek, Nico M Wulffraat, Saskia M F Pluijm, Robert de Jonge

Journal:

Pediatric Rheumatology

Year:

2011

Language:

english

File:

PDF, 84 KB

english, 2011

22

Prediction of clinical non-response to methotrexate treatment in juvenile idiopathic arthritis

EH Pieter Van Dijkhuizen, Maja Bulatović, Marloes W Heijstek, Nico M Wulffraat, Saskia MF Pluijm, Robert de Jonge

Journal:

Pediatric Rheumatology

Year:

2011

Language:

english

File:

PDF, 84 KB

english, 2011

23

Methotrexate restores effector T cell responsiveness in juvenile idiopathic arthritis

Maja Bulatović, Sebastiaan Vastert, Frederik Verweij, Nico Wulffraat, Femke van Wijk, Berent Prakken

Journal:

Pediatric Rheumatology

Year:

2011

Language:

english

File:

PDF, 99 KB

english, 2011

24

Fatal hemophagocytic lymphohistiocytosis in X-linked chronic granulomatous disease associated with a perforin gene variant

Joris M. van Montfrans, Eva Rudd, Lisette van de Corput, Jan-Inge Henter, Peter Nikkels, Nico Wulffraat, Jaap J. Boelens

Journal:

Pediatric Blood & Cancer

Year:

2009

Language:

english

File:

PDF, 73 KB

english, 2009

25

Awareness of Fabry disease among rheumatologists—current status and perspectives

Rolando Cimaz, Severine Guillaume, Max J. Hilz, Gerd Horneff, Bernhard Manger, J. Carter Thorne, Anette Torvin Møller, Nico M. Wulffraat, Johannes Roth

Journal:

Clinical Rheumatology

Year:

2011

Language:

english

File:

PDF, 335 KB

english, 2011

26

Autologous hemopoietic stem-cell transplantation for children with refractory autoimmune disease

Nico M. Wulffraat, Lieke AM Sanders, Wietse Kuis

Journal:

Current Rheumatology Reports

Year:

2000

Language:

english

File:

PDF, 342 KB

english, 2000

27

Les cellules souches mésenchymateuses : un futur traitement des arthrites ?

Joost Swart, Anton Martens, Nico Wulffraat

Journal:

Revue du Rhumatisme

Year:

2008

Language:

french

File:

PDF, 104 KB

french, 2008

28

Arthrite réactionnelle après infection par Clostridium difficile chez deux enfants

Helga A Löffer, Benedicte Pron, Richard Mouy, Nico M Wulffraat, Anne-Marie Prieur

Journal:

Revue du Rhumatisme

Year:

2004

Language:

french

File:

PDF, 114 KB

french, 2004

29

10.1038/76024

de Saint Basile, Geneviève, Ménasché, Gaël, Pastural, Elodie, Feldmann, Jérôme, Certain, Stéphanie, Ersoy, Fügen, Dupuis, Sophie, Wulffraat, Nico, Bianchi, Diana, Fischer, Alain, Le Deist, Françoise

Journal:

Nature Genetics

Year:

2000

Language:

english

File:

PDF, 208 KB

english, 2000

30

F.59. Autologous Bone Marrow Transplantation Induces Immune Tolerance in Proteoglycan Induced Arthritis by Restoring the Immune Balance Between Regulation and Inflammation

Sarah Roord, Wilco de Jager, Anton Martens, Nico Wulffraat, Berent Prakken, Femke van Wijk

Journal:

Clinical Immunology

Year:

2009

Language:

english

File:

PDF, 35 KB

english, 2009

31

Mesenchymal stem cells: A future for the treatment of arthritis?

Joost Swart, Anton Martens, Nico Wulffraat

Journal:

Joint Bone Spine

Year:

2008

Language:

english

File:

PDF, 126 KB

english, 2008

32

Stress induces increases in IL-6 production by leucocytes of patients with the chronic inflammatory disease juvenile rheumatoid arthritis: a putative role for α1-adrenergic receptors

Charlotte Roupe van der Voort, Cobi J. Heijnen, Nico Wulffraat, Wietse Kuis, Annemieke Kavelaars

Journal:

Journal of Neuroimmunology

Year:

2000

Language:

english

File:

PDF, 229 KB

english, 2000

33

Clostridium difficile-associated reactive arthritis in two children

Helga A. Löffler, Benedicte Pron, Richard Mouy, Nico M. Wulffraat, Anne-Marie Prieur

Journal:

Joint Bone Spine

Year:

2004

Language:

english

File:

PDF, 109 KB

english, 2004

34

Stem cells in pediatrics: state of the art and future perspectives

Heijnen, Cobi J., Witt, Olaf, Wulffraat, Nico, Kulozik, Andreas E.

Journal:

Pediatric Research

Year:

2012

Language:

english

File:

PDF, 225 KB

english, 2012

35

Two Genes Are Responsible for Griscelli Syndrome at the Same 15q21 Locus

Elodie Pastural, Fügen Ersoy, Nevin Yalman, Nico Wulffraat, Eugênio Grillo, Ferda Ozkinay, Ilhan Tezcan, G. Gediköglu, Noël Philippe, Alain Fischer, Geneviève de Saint Basile

Journal:

Year:

2000

Language:

english

File:

PDF, 116 KB

english, 2000

36

Survival in a Recent Cohort of Mechanically Ventilated Pediatric Allogeneic Hematopoietic Stem Cell Transplantation Recipients

Josephus P.J. van Gestel, Casper W. Bollen, Marc B. Bierings, Jaap Jan Boelens, Nico M. Wulffraat, Adrianus J. van Vught

Journal:

Biology of Blood and Marrow Transplantation

Year:

2008

Language:

english

File:

PDF, 257 KB

english, 2008

37

Prevalence of circulating immune complexes in patients with cystic fibrosis and arthritis

Nico M. Wulffraat, Elisabeth R. de Graeff-Meeder, Ger T. Rijkers, Han van der Laag, Wietse Kuis

Journal:

The Journal of Pediatrics

Year:

1994

Language:

english

File:

PDF, 394 KB

english, 1994

38

Autologous haemopoietic stem-cell transplantation in four patients with refractory juvenile chronic arthritis

Nico Wulffraat, Annet van Royen, Marc Bierings, Jaak Vossen, Wietse Kuis

Journal:

Year:

1999

Language:

english

File:

PDF, 68 KB

english, 1999

39

Functional α1-adrenergic receptors on leukocytes of patients with polyarticular juvenile rheumatoid arthritis

Cobi J. Heijnen, Charlotte Rouppe van der Voort, Nico Wulffraat, Janjaap van der Net, Wietse Kuis, Annemieke Kavelaars

Journal:

Journal of Neuroimmunology

Year:

1996

Language:

english

File:

PDF, 786 KB

english, 1996

40

Refractory juvenile idiopathic arthritis

Nico M Wulffraat, Ismee M de Kleer, Berent J Prakken, Wietse Kuis

Journal:

Best Practice & Research Clinical Haematology

Year:

2004

Language:

english

File:

PDF, 200 KB

english, 2004

41

Aerobic capacity and disease activity in children, adolescents and young adults with juvenile idiopathic arthritis (JIA)

Philomien A van Pelt, Tim Takken, Marco van Brussel, Inge de Witte, Aike A Kruize, Nico M Wulffraat

Journal:

Pediatric Rheumatology

Year:

2012

Language:

english

File:

PDF, 288 KB

english, 2012

42

Aerobic capacity and disease activity in children, adolescents and young adults with juvenile idiopathic arthritis (JIA)

Philomine A van Pelt, Tim Takken, Marco van Brussel, Mirjam de Witte, Aike A Kruize, Nico M Wulffraat

Journal:

Pediatric Rheumatology

Year:

2012

Language:

english

File:

PDF, 267 KB

english, 2012

43

Canakinumab in pediatric rheumatic diseases

Wulffraat, Nico M, Woo, Patricia

Journal:

Expert Opinion on Biological Therapy

Year:

2013

Language:

english

File:

PDF, 343 KB

english, 2013

44

Translational medicine from bedside to bench and back again: methotrexate revisited

Ćalasan, Maja Bulatović, Thurlings, Rogier M, Wulffraat, Nico M, Prakken, Berent J

Journal:

International Journal of Clinical Rheumatology

Year:

2013

Language:

english

File:

PDF, 1.69 MB

english, 2013

45

Time to share

Nico M Wulffraat, Bas Vastert

Journal:

Pediatric Rheumatology

Year:

2013

Language:

english

File:

PDF, 258 KB

english, 2013

46

Antibody deficiency in patients with ataxia telangiectasia is caused by disturbed B- and T-cell homeostasis and reduced immune repertoire diversity

Driessen, Gertjan J., IJspeert, Hanna, Weemaes, Corry M.R., Haraldsson, Ásgeir, Trip, Margreet, Warris, Adilia, van der Flier, Michiel, Wulffraat, Nico, Verhagen, Mijke M.M., Taylor, Malcolm A., van Z

Journal:

Journal of Allergy and Clinical Immunology

Year:

2013

Language:

english

File:

PDF, 755 KB

english, 2013

47

Assessment of disease activity by patients with juvenile idiopathic arthritis and the parents compared to the assessment by pediatric rheumatologists

Armbrust, Wineke, Kaak, Jolanda G, Bouma, Jelte, Lelieveld, Otto T H M, Wulffraat, Nico M, Sauer, Pieter J J, van Sonderen, Eric

Journal:

Pediatric Rheumatology

Year:

2013

Language:

english

File:

PDF, 244 KB

english, 2013

48

Prevalence of methotrexate intolerance in rheumatoid arthritis and psoriatic arthritis

Bulatović Ćalasan, Maja, van den Bosch, Oscar FC, Creemers, Marjonne CW, Custers, Martijn, Heurkens, Antonius HM, van Woerkom, Jan, Wulffraat, Nico M

Journal:

Arthritis Research & Therapy

Year:

2013

Language:

english

File:

PDF, 153 KB

english, 2013

49

A6: Tapering and Withdrawal of Tocilizumab in Patients With Systemic Juvenile Idiopathic Arthritis in Inactive Disease: Results From an Alternative Dosing Regimen in the TENDER Study

De Benedetti, Fabrizio, Ruperto, Nicolino, Brunner, Hermine, Grom, Alexei A., Wulffraat, Nico, Henrickson, Michael, Jerath, Rita, Kimura, Yuki, Kadva, Alysha K., Wang, Jianmei, Martini, Alberto, Lovel

Journal:

Arthritis & Rheumatology

Year:

2014

Language:

english

File:

PDF, 39 KB

english, 2014

50

Biologic treatment of pediatric rheumatic diseases: are we spoilt for choice?

van Royen-Kerkhof, Annet, Vastert, Bas SJ, Swart, Joost F, Wulffraat, Nico M

Journal:

Year:

2014

Language:

english

File:

PDF, 495 KB

english, 2014

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